Relative apical sparing of longitudinal strain using two-dimensional speckle-tracking echocardiography is both sensitive and specific for the diagnosis of cardiac amyloidosis
Why the study?
Is relative apical sparing of longitudinal strain using two-dimensional speckle-tracking echocardiography sensitive and specific for diagnosing cardiac amyloidosis?
Population
Patients with cardiac amyloidosis (CA) or other causes of left ventricular hypertrophy
Design
Other
Authors
Discussion
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Member takes
Implication
May aid differentiation of cardiac amyloidosis among LV hypertrophy cases; leaves open prospective validation in unselected populations.
Structured PICO
Is relative apical sparing of longitudinal strain using two-dimensional speckle-tracking echocardiography sensitive and specific for diagnosing cardiac amyloidosis?
P
Population
Patients with cardiac amyloidosis (CA) or other causes of left ventricular hypertrophy
I
Intervention
Two-dimensional speckle-tracking echocardiography to assess relative 'apical sparing' pattern of longitudinal strain (LS)
O
Outcome
Differentiation of cardiac amyloidosis from other causes of LV hypertrophy (diagnostic sensitivity and specificity)surrogate
Relative apical sparing of longitudinal strain on 2D speckle-tracking echocardiography is an accurate and reproducible marker for diagnosing cardiac amyloidosis.
Cite This Study
Phelan et al. (2012) studied this question.