Why the study?
Does MRTF-A regulate myofibroblast activation and fibrosis post-myocardial infarction?
Does MRTF-A regulate myofibroblast activation and fibrosis post-myocardial infarction?
MRTF-A plays a regulatory role in myofibroblast activation and fibrosis following myocardial infarction.
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Hypothesis-generating for MRTF-A inhibition to limit post-MI fibrosis; leaves open clinical translation in patients.
Small et al. (2010) studied this question.
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