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January 17, 2022Open Forum Infectious Diseases48 citationsOpen Access

Trimethoprim-Sulfamethoxazole Versus Levofloxacin for Stenotrophomonas maltophilia Infections: A Retrospective Comparative Effectiveness Study of Electronic Health Records from 154 US Hospitals

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SSSadia SarzynskiNational Heart Lung and Blood InstituteSWSarah WarnerNational Heart Lung and Blood InstituteJSJunfeng SunKunming University of Science and Technology

Key Points

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Abstract

Based on observational evidence, levofloxacin is a reasonable alternative to TMP-SMX for the treatment of bloodstream and lower respiratory tract infections caused by S maltophilia.

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Cite This Study

Sarzynski et al. (2022) studied this question.

synapsesocial.com/papers/69df0898d85e58e37b7a0e1fhttps://doi.org/10.1093/ofid/ofab644
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Impact of Initial Antimicrobial Therapy in Patients with Bloodstream Infections Caused by Stenotrophomonas maltophilia2005 · 30 citations
  2. 2Microbiological and Clinical Aspects of Infection Associated with Stenotrophomonas maltophilia1998 · 853 citations
  3. 3Efficacy and safety of cefiderocol or best available therapy for the treatment of serious infections caused by carbapenem-resistant Gram-negative bacteria (CREDIBLE-CR): a randomised, open-label, multicentre, pathogen-focused, descriptive, phase 3 trial2020 · 826 citations
  4. 4Adverse events of fluoroquinolones vs. other antimicrobials prescribed in primary care: A systematic review and meta-analysis of randomized controlled trials2018 · 73 citations
  5. 5Monotherapy with Fluoroquinolone or Trimethoprim-Sulfamethoxazole for Treatment of Stenotrophomonas maltophilia Infections2013 · 128 citations