Why the study?
Does new NSAID use increase the risk of acute kidney injury and hyperkalemia in older adults?
Does new NSAID use increase the risk of acute kidney injury and hyperkalemia in older adults?
New NSAID use in older adults is associated with an increased short-term risk of acute kidney injury and hyperkalemia, emphasizing the need for individualized risk assessment before prescribing.
Answers are grounded in this paper and cite their sources.
May warrant caution with new NSAID prescriptions in older adults; leaves open whether risks are causal or persist long-term.
In older adults, new NSAID use compared with nonuse was associated with a higher 30-day risk of AKI and hyperkalemia but not all-cause mortality. Prescription NSAID use among many older adults may be safe, but providers should use caution and assess individual risk.
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Nash et al. (2019) studied this question.
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