Detection and characteristics of microvascular obstruction in reperfused acute myocardial infarction using an optimized protocol for contrast-enhanced cardiovascular magnetic resonance imaging
Why the study?
Does an optimized 3D IR-GRE CMR protocol accurately detect early and late microvascular obstruction and correlate with left ventricular remodeling in patients with reperfused AMI?
Population
84 consecutive patients with a reperfused acute myocardial infarction (AMI)
Design
Cohort
Follow-up
average 5 and 104 days after admission
Authors
Discussion
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Member takes
Implication
May guide CMR timing for MVO assessment in AMI; leaves open remodeling prediction utility.
Structured PICO
Does an optimized 3D IR-GRE CMR protocol accurately detect early and late microvascular obstruction and correlate with left ventricular remodeling in patients with reperfused AMI?
P
Population
84 consecutive patients with a reperfused acute myocardial infarction (AMI)
I
Intervention
Optimised single breath-hold 3D inversion recovery gradient echo pulse sequence (IR-GRE) protocol for contrast-enhanced cardiovascular magnetic resonance imaging (CMR)
O
Outcome
Prevalence of microvascular obstruction (MVO) and dynamic changes in its appearancesurrogate
An optimized single breath-hold 3D IR-GRE CMR technique effectively detects early and late microvascular obstruction, which correlates with left ventricular remodeling in reperfused AMI.
Cite This Study
Bekkers et al. (2009) studied this question.