Population
Chimeric myosin models
Design
Preclinical
Authors
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No immediate clinical implications for myosinopathies; extends chimeric mapping of loop 1-ADP effects but leaves translation open.
The sequence of specific surface loops on myosin, such as the 50-20K loop, influences its affinity for actin and maximum ATPase activity.
Murphy et al. (1999) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: