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April 1, 2000Journal of Lipid ResearchOpen Access

Peroxisome proliferator-activated receptor α (PPARα) and agonist inhibit cholesterol 7α-hydroxylase gene (CYP7A1) transcription

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Authors

MMMaria MarrapodiOhio UniversityJCJohn Y.L. ChiangNortheast Ohio Medical University

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Marrapodi et al. (2000) studied this question.

synapsesocial.com/papers/69df2517d9e0feb21c591bcchttps://doi.org/10.1016/s0022-2275(20)32398-1
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Mode of Action of Peroxisome Proliferators as Hypolipidemic Drugs.1995 · 340 citations
  2. 2Targeted Disruption of the α Isoform of the Peroxisome Proliferator-Activated Receptor Gene in Mice Results in Abolishment of the Pleiotropic Effects of Peroxisome Proliferators1995 · 1,668 citations
  3. 3Isolation and structural characterization of the rat acyl-CoA oxidase gene.1987 · 102 citations
  4. 4HNF4 and COUP-TFII interact to modulate transcription of the cholesterol 7α-hydroxylase gene (CYP7A1)2000 · 147 citations
  5. 5Alterations in Lipoprotein Metabolism in Peroxisome Proliferator-activated Receptor α-deficient Mice1997 · 432 citations