Key result
Arteriovenous loop facilitates transseptal mitral ViV implantation when massive biatrial enlargement precludes standard delivery.
Why the study?
During transseptal mitral valve-in-valve implantation for failed surgical bioprostheses, massive biatrial enlargement can preclude delivery and lead to procedural failure.
Does the full-body rail technique enable successful transseptal mitral valve-in-valve implantation in patients with massive biatrial enlargement?
Case Report (n=1)
Does the full-body rail technique enable successful transseptal mitral valve-in-valve implantation in patients with massive biatrial enlargement?
The full-body rail technique is a viable bailout strategy for transseptal mitral valve-in-valve implantation in patients with massive biatrial enlargement and horizontal septal-annular angles.
May enable transseptal MVIV despite massive biatrial enlargement; extends feasibility and leaves open generalizability.
BACKGROUND: Transseptal mitral valve-in-valve (ViV) implantation is an established therapy for failed surgical bioprostheses. However, massive biatrial enlargement can preclude delivery, leading to procedural failure. CASE SUMMARY: A 75-year-old woman presented with heart failure after surgical mitral bioprosthesis implantation. Echocardiography revealed severe mitral bioprosthetic failure and massive biatrial enlargement. Computed tomography angiography showed a septal-annular angle of 106°. During the procedure, the stiff wire and the delivery system repeatedly prolapsed into the giant atrium. A full-body rail was created by snaring the guidewire from the femoral artery, providing adequate support. Then a 23-mm SAPIEN 3 valve was successfully deployed. Postprocedural mean gradient decreased to 4 mm Hg with mild paravalvular leak. The patient recovered uneventfully with significant functional improvement. DISCUSSION: The full-body rail technique is a critical bailout strategy for mitral ViV in patients with massive atria, enabling coaxial alignment and safe delivery. TAKE-HOME MESSAGES: Massive biatrial enlargement and a horizontal septal-annular angle (>100°) can preclude standard delivery during mitral ViV implantation. The step-by-step creation of a full-body (arteriovenous) rail is a rescue technique to stabilize the delivery system.
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Li et al. (2026) conducted a case report in Severe mitral bioprosthetic failure with massive biatrial enlargement (n=1). Transseptal mitral valve-in-valve implantation using a full-body (arteriovenous) rail technique was evaluated on Postprocedural mean gradient. Transseptal mitral valve-in-valve implantation using a full-body arteriovenous rail technique was successfully performed in a patient with massive biatrial enlargement, reducing the mean gradient to 4 mm Hg.
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