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April 15, 2026Journal of Liver TransplantationOpen Access

Adult T-cell leukemia/ lymphoma occurring 15 years after liver transplantation: A case report and literature review

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Authors

HHHeng-Yen HoYHYung Lin HsiehSYShan-Chi Yu

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Overview

A case report observes adult T-cell leukemia/lymphoma after liver transplantation, highlighting the need for careful monitoring.

Key Points

  • To report a rare case of adult T-cell leukemia/lymphoma (ATLL) occurring 15 years post liver transplantation.
  • Case report of a 69-year-old man with ATLL after liver transplantation for hepatocellular carcinoma.
  • Diagnosis included imaging studies, bone marrow analysis, and HTLV-1 testing.
  • Treatment involved chemotherapy, intrathecal therapy, and stem cell transplantation.
  • The patient developed advanced ATLL 15 years post-liver transplantation, marking the longest latency reported.
  • Despite treatment, the patient faced severe complications and died 11 months post-diagnosis.
  • The case suggests a need for vigilance and monitoring in HTLV-1 carriers after liver transplantation.

Cite This Study

Ho et al. (2026) studied this question.

synapsesocial.com/papers/69df2a4be4eeef8a2a6af900https://doi.org/10.1016/j.liver.2026.100349
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Atypical Presentation for Adult T-Cell Leukemia/Lymphoma: a Case Report and Short Review of the Literature2024
  2. 2Lymphomatous-type adult T-cell leukemia/lymphoma associated with HTLV-1 presenting as chronic respiratory illness in a young adult: a case report2026
  3. 3Outcomes of patients with adult T-cell leukemia/lymphoma at a university and a public cancer center in Brazil2026
  4. 4[Prevention and treatment of post-transplant relapse in adult T-cell leukemia-lymphoma].2025
  5. 5Clinical Features and Survival Outcome in Aggressive-Type Adult T-Cell Leukemia/Lymphoma Patients: Real-Life Experience of a Single Center from an HTLV-1 Endemic Country2024 · 1 citations