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April 15, 2026Future Science OA2 citationsOpen Access

Ultrasound-guided injection strategies for lateral epicondylitis: a multicenter randomized comparison of corticosteroid, platelet-rich plasma, and ozone

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SRSeyed Ahmad RaeissadatDADavood Khavari ArdestaniShahid Beheshti University of Medical SciencesSMSeyyede Elahe MousavikhahShahid Beheshti University of Medical Sciences

Key Points

  • This research aims to compare the effectiveness of corticosteroid, platelet-rich plasma, and ozone injections for treating lateral epicondylitis.
  • Multicenter randomized trial design
  • Participants received one of three treatments: corticosteroid, low-leukocyte PRP, or ozone
  • Evaluated pain and function at 6 months post-injection
  • All three treatment options improved pain and function at 6 months
  • No single injection type was statistically superior to the others
  • Treatment choice should involve patient preferences and costs

Abstract

Ultrasound-guided injections of corticosteroid, low-leukocyte PRP, and ozone are all effective treatments for improving pain and function in patients with chronic lateral epicondylitis at 6 months. As no single agent proved statistically superior, the choice of therapy should be guided by a process of shared decision-making that considers factors such as patient preference, cost, and desired timeline for relief.

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Cite This Study

Raeissadat et al. (2026) studied this question.

synapsesocial.com/papers/69df2abce4eeef8a2a6afc9ahttps://doi.org/10.1080/20565623.2026.2644326
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