Radical Ring-Opening Polymerization-Induced Self-Assembly for the Synthesis of Degradable Particles Incorporating Ethyl Lipoate

Fan Yang; Jacinta White; Yufu Wang; Yanting Gao; Daniel Yuen; Angus Philip Raynor Johnston; Almar Postma; Lewis D. Blackman; Georgina Kate Such

doi:10.1039/d6py00218h

January 1, 2026Polymer Chemistry

Radical Ring-Opening Polymerization-Induced Self-Assembly for the Synthesis of Degradable Particles Incorporating Ethyl Lipoate

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Key Points

The research aims to explore the use of radical ring-opening polymerization for creating degradable particles via self-assembly.
Utilized radical ring-opening polymerization to synthesize polymers.
Employed polymerization-induced self-assembly (PISA) for nanoparticle formation.
Evaluated the cargo protection and release capabilities of the synthesized nanoparticles.
Successful creation of polymeric nanoparticles with enhanced bioavailability.
Demonstrated controlled release of cargo from the nanoparticles.
Particles showed degradability, enhancing their potential for biomedical applications.

Implication

The study demonstrates how polymerization-induced self-assembly synthesizes degradable particles, suggesting advancements in cargo delivery systems.

Abstract

Polymeric nanoparticles are widely used in biomedical applications due to their ability to protect cargo, enhance bioavailability and enable controlled cargo release. Polymerization-induced self-assembly (PISA) is a versatile and scalable...

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Cite This Study

Yang et al. (2026) studied this question.

synapsesocial.com/papers/69df2ae6e4eeef8a2a6afe8d https://doi.org/10.1039/d6py00218h

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Radical Ring-Opening Polymerization-Induced Self-Assembly for the Synthesis of Degradable Particles Incorporating Ethyl Lipoate

Key Points

Implication

Abstract

Discussion

Cite This Study

Radical Ring-Opening Polymerization-Induced Self-Assembly for the Synthesis of Degradable Particles Incorporating Ethyl Lipoate

Key Points

Implication

Abstract

Discussion

Cite This Study

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