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April 15, 2026Journal of Ultrasound in Medicine2 citationsOpen Access

Fetal Heart Rate at 12 Weeks' Gestation and the Risk of Preterm Birth

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JMJosé Morales‐RosellóUniversitat de ValènciaASAlicia Soriano-PayáHospital Universitario Doctor PesetBÁBlanca Novillo-Del ÁlamoUniversidad Cardenal Herrera CEU

Key Points

  • This research examines the relationship between fetal heart rate at 12 weeks and the risk of preterm birth.
  • Analyzed fetal heart rate measurements at the 12-week scan.

Structured PICO

Does elevated fetal heart rate at 12 weeks' gestation predict spontaneous preterm birth?

P
Population
Pregnancies undergoing a 12-week scan
I
Intervention
Elevated fetal heart rate (FHR), potentially combined with free-βhCG
O
Outcome
Spontaneous preterm birth (sPTB), particularly before 34 weeks' gestationhard clinical

Elevated fetal heart rate at 12 weeks' gestation may serve as an early first-trimester screening marker for spontaneous preterm birth.

Abstract

Elevated FHR at the 12-week scan is associated with sPTB, particularly before 34 weeks' gestation. FHR, especially when combined with free-βhCG, may contribute to early first-trimester screening strategies for sPTB.

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Cite This Study

Morales‐Roselló et al. (2026) studied this question.

synapsesocial.com/papers/69df2b04e4eeef8a2a6b00bahttps://doi.org/10.1002/jum.70252
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