What question did this study set out to answer?

The research aims to address the overlooked role of improper pharmaceutical disposal in contributing to antimicrobial resistance within the One Health framework.

April 15, 2026mSphereOpen Access

The missing thread of One Health efforts: improper drug disposal as an overlooked driver of antimicrobial resistance

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Authors

SMSandip Mukhopadhyay FDFalguni DebnathNational Institute of Epidemiology DCDebjit ChakrabortyNational Remote Sensing Centre

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Implication

The study highlights improper pharmaceutical disposal's impact on antimicrobial resistance, suggesting a need for better waste management strategies.

Key Points

The research aims to address the overlooked role of improper pharmaceutical disposal in contributing to antimicrobial resistance within the One Health framework.
Examined the impact of discarded antimicrobials on environmental microbes
Analyzed the flow of pharmaceutical residues in various ecosystems
Reviewed evidence from India and other low and middle-income countries
Improper disposal leads to environmental exposure to sub-inhibitory concentrations of antimicrobials.
Resistant bacteria emerge and persist due to selective pressure from environmental residues.
Clinically significant resistance genes were found in non-clinical environments.
Household pharmaceutical waste management is largely absent from AMR action plans.

Cite This Study

Mukhopadhyay et al. (2026) studied this question.

synapsesocial.com/papers/69df2b2ce4eeef8a2a6b00f9 https://doi.org/10.1128/msphere.00586-25

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Implication

The study highlights improper pharmaceutical disposal's impact on antimicrobial resistance, suggesting a need for better waste management strategies.

The missing thread of One Health efforts: improper drug disposal as an overlooked driver of antimicrobial resistance

Discussion

Member takes

Implication

Key Points

Cite This Study

The missing thread of One Health efforts: improper drug disposal as an overlooked driver of antimicrobial resistance

Discussion

Member takes

Implication

Key Points

Cite This Study

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