Robot-Assisted Liver Resection With Versius ® Surgical System: COMPAR-L Prospective Study

Background While similar procedures can be performed using various robotic platforms across different surgical fields, no data exists on robotic liver resection (RLR) with the Versius ® robotic system (Cambridge Medical Robots-CMR Surgical). This study collected data on the first case series of hepatectomies using the Versius ® system. Methods Patients who underwent liver resection of anterolateral segments using the Versius ® system at the General and Hepatobiliary Surgery unit of the University of Verona between July and December 2024 were enrolled. Experienced surgeons in RLR performed the resections. The short-term outcomes, timing, and cost of each surgical and non-surgical phase were analyzed. Results Ten patients underwent robotic liver resection using the Versius ® platform for hepatocellular carcinoma (n = 2), liver metastases (n = 2), and benign lesions (n = 6) in the anterolateral segments. Eight patients had prior abdominal surgery, 2 had multiple lesions, and 6 had anatomical resections (ie, H23 n = 3, H2 n = 1, H3 n = 1, H5-subsegmentectomy n = 1). Hilar clamping was used in 5 patients, with a median total time of 30 min (IQR 15-40), median blood loss of 50.0 mL (IQR 50.0-100.0), and no intra- or post-operative complications. Median total operative time was 259.5min (IQR 183.0-347.0) with median parenchymal transection time of 83.0min (IQR 40.8-93.8). Median total cost of the procedure was €4146.5 (IQR 3608.5-4976.2), which included personnel, operating room, robotic platform, kit, and consumables costs. Conclusions This preliminary experience with liver resection using the Versius ® system demonstrated its feasibility and safety. To our knowledge, this is the first reported series of liver resections utilizing the Versius ® platform.