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April 15, 2026RSC AdvancesOpen Access

NHC-catalyzed asymmetric synthesis of natural products and pharmaceutical drugs

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Authors

ASAfifa ShahidSKSamreen Gul KhanMSMuhammad Jawwad Saif

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Overview

This review highlights NHCs' role in synthesizing natural products and drugs, suggesting their potential for pharmaceuticals.

Key Points

  • To explore the applications of N-heterocyclic carbenes in synthesizing natural products and drugs.
  • Reviewed recent literature on NHC applications in synthesis.
  • Analyzed various methodologies and outcomes in natural products synthesis.
  • Examined the pharmaceutical relevance of NHC-catalyzed reactions.
  • NHCs were found effective in asymmetric synthesis processes.
  • Multiple natural products were successfully synthesized using NHCs.
  • NHC-catalyzed methods showcased significant efficiency in drug development.

Cite This Study

Shahid et al. (2026) studied this question.

synapsesocial.com/papers/69df2b2ce4eeef8a2a6b0212https://doi.org/10.1039/d5ra10073a
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