NHC-catalyzed asymmetric synthesis of natural products and pharmaceutical drugs

Afifa Shahid; Samreen Gul Khan; Muhammad Jawwad Saif; Ameer Fawad Zahoor; Bushra Parveen; Aqsa Mushtaq; Asim Mansha; Arif Mermer; Aijaz Rasool Chaudhry; Ahmad Irfan

doi:10.1039/d5ra10073a

January 1, 2026RSC AdvancesOpen Access

NHC-catalyzed asymmetric synthesis of natural products and pharmaceutical drugs

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Key Points

To explore the applications of N-heterocyclic carbenes in synthesizing natural products and drugs.
Reviewed recent literature on NHC applications in synthesis.
Analyzed various methodologies and outcomes in natural products synthesis.
Examined the pharmaceutical relevance of NHC-catalyzed reactions.
NHCs were found effective in asymmetric synthesis processes.
Multiple natural products were successfully synthesized using NHCs.
NHC-catalyzed methods showcased significant efficiency in drug development.

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Implication

This review highlights NHCs' role in synthesizing natural products and drugs, suggesting their potential for pharmaceuticals.

Abstract

This review article entails the recent applications of N -heterocyclic carbenes (NHCs) towards the synthesis of natural products and pharmaceutical drugs.

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Cite This Study

Shahid et al. (2026) studied this question.

synapsesocial.com/papers/69df2b2ce4eeef8a2a6b0212 https://doi.org/10.1039/d5ra10073a

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NHC-catalyzed asymmetric synthesis of natural products and pharmaceutical drugs

Key Points

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Implication

Abstract

Discussion

Cite This Study

NHC-catalyzed asymmetric synthesis of natural products and pharmaceutical drugs

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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