Profiling of syngeneic mouse HCC tumor models as a framework to understand anti–PD‐1 sensitive tumor microenvironments

Daniel J. Zabransky; Ludmila Danilova; James M. Leatherman; Tamara Y. Lopez‐Vidal; Jessica I. Sanchez; Soren Charmsaz; Nicole Groß; Sarah M. Shin; Xuan Yuan; Alexei Hernandez; Hongqui Yang; Stephanie Xavier; Daniel Shu; A.I. Saeed; Kabeer Munjal; Zeal Kamdar; Luciane T. Kagohara; Elizabeth M. Jaffee; Mark Yarchoan; Won Jin Ho

doi:10.1002/hep.32707

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Abstract

There is a wide diversity in the immune tumor microenvironments in preclinical models and in human HCC, highlighting the need to use multiple syngeneic HCC models to improve the understanding of how to treat HCC through immune modulation.

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Zabransky et al. (2022) studied this question.

synapsesocial.com/papers/69df2b39d85e58e37b7a18fc https://doi.org/10.1002/hep.32707

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Profiling of syngeneic mouse HCC tumor models as a framework to understand anti–PD‐1 sensitive tumor microenvironments

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Profiling of syngeneic mouse HCC tumor models as a framework to understand anti–PD‐1 sensitive tumor microenvironments

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