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April 15, 2026World Journal of UrologyOpen Access

Vardenafil in the multidisciplinary management of erectile dysfunction: a narrative review on multidimensional outcomes and clinical integration

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Authors

JZJiedong Zhou†SHShian HuFirst Affiliated Hospital of Gannan Medical UniversityYOYong OuyangFirst Affiliated Hospital of Gannan Medical University

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Implication

A narrative review explores vardenafil's impact on erectile dysfunction, suggesting promising clinical integration implications.

Key Points

  • This review synthesizes evidence on vardenafil’s pharmacological mechanisms and clinical efficacy in managing erectile dysfunction.
  • Comprehensive literature search in PubMed, Web of Science, and Embase.
  • Review of randomized controlled trials, cohort studies, and mechanistic studies.
  • Narrative synthesis of findings across various intervention domains.
  • Vardenafil shows favorable short-term efficacy for multiple causes of erectile dysfunction.
  • Efficacy is supported as a monotherapy and with testosterone, psychological interventions, and lifestyle changes.
  • Heterogeneity of studies limits the robustness of evidence but indicates potential benefits in multidisciplinary settings.

Cite This Study

Zhou† et al. (2026) studied this question.

synapsesocial.com/papers/69df2b49e4eeef8a2a6b03c2https://doi.org/10.1007/s00345-026-06391-4
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