Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
April 15, 2026Journal of Gastroenterology and HepatologyOpen Access

Immune Evasion of Helicobacter pylori and Extra‐Gastric Cancer Risk

View Full Paper
Ask AI
Bookmark
Share

Authors

EEEvren Doruk EnginAEAyse Basak EnginAEAyse Basak Engin

Discussion

Loading...

Member takes

Overview

This research uncovers immune evasion mechanisms leading to extra-gastric cancer risk associated with H. pylori infection, indicating clinical significance in cancer pathology.

Key Points

  • The aim is to explore how H. pylori's immune evasion contributes to extra-gastric cancer development.
  • Analyzed the role of H. pylori in extra-gastric cancers.
  • Investigated virulence factors associated with H. pylori strains.
  • Examined intercellular communication via exosomes in H. pylori-infected cells.
  • Evaluated kynurenine production and its effects on immune suppression.
  • H. pylori infection is linked to various extra-gastric cancers.
  • Higher kynurenine levels were found in H. pylori seropositive patients.
  • Immune suppression via kynurenine promotes tumor cell growth and survival.

Cite This Study

Engin et al. (2026) studied this question.

synapsesocial.com/papers/69df2b85e4eeef8a2a6b082chttps://doi.org/10.1111/jgh.70376
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Beyond the stomach: the association between Helicobacter pylori and the spectrum of digestive cancers2025
  2. 2Strategies of Helicobacter pylori in evading host innate and adaptive immunity: insights and prospects for therapeutic targeting2024 · 21 citations
  3. 3Association between<i>Helicobacter pylori</i>and its eradication and the development of cancer2024 · 4 citations
  4. 4Impact of Helicobacter pylori infection on gut and intratumoral microbiome and its association with immunotherapy response in gastrointestinal cancer2026 · 9 citations
  5. 5Editorial: The gut microbiome's role in gastric cancer: mechanisms and therapies2026