Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
April 15, 2026Journal of Cardiothoracic SurgeryOpen Access

Excision of complex calcified LA myxomas yields contrasting outcomes from successful repair to fatal multiorgan failure.

View Full Paper
Ask AI
Bookmark
Share

Why the study?

Complex atrial myxomas involving adjacent valvular or septal structures may lead to challenging repairs and adverse outcomes.

What are the surgical outcomes and potential complications of excising complex, calcified left atrial myxomas?

Population

Two patients with calcified left atrial myxomas

Design

Case series

Key result

Surgical excision of complex, calcified left atrial myxomas encroaching on the mitral annulus resulted in contrasting outcomes in two patients, ranging from successful repair to fatal multiorgan failure.

Authors

MLMarco LizwanSESee Hooi EweSTSamuel Jun Wei Tho

Discussion

Loading...

Member takes

Overview

Requires meticulous planning to avoid structural and conduction complications; leaves open optimal resection strategies for calcified myxomas near the mitral annulus.

Key Points

  • This research aims to explore the complexities and outcomes of surgical excision of calcified atrial myxomas.
  • Two case studies of patients with atrial myxomas
  • Preoperative imaging and intraoperative assessment employed
  • Surgical interventions included annuloplasty and patch reinforcement
  • One patient had successful resection and excellent recovery with preserved mitral stability
  • Another patient experienced severe complications, including heart block and valve perforation leading to death
  • Contrasting outcomes highlight risks associated with complex tumors near critical cardiac structures

Study Design

Type

Case Report (n=2)

Multicenter

No

Structured PICO

What are the surgical outcomes and potential complications of excising complex, calcified left atrial myxomas?

P
Population
2 patients (a 72-year-old woman and a 68-year-old man) with calcified left atrial myxomas
I
Intervention
Surgical resection of calcified left atrial myxoma
O
Outcome
Surgical outcomes and complicationshard clinical

Excision of complex, calcified left atrial myxomas near the mitral annulus or atrioventricular septum can lead to severe structural and conduction complications, highlighting the need for meticulous surgical planning.

Limitations

  • Small sample size inherent to a case report of two patients, limiting generalizability.

Cite This Study

Lizwan et al. (2026) conducted a case report in Calcified left atrial myxoma (n=2). Surgical excision was evaluated. Surgical excision of complex, calcified left atrial myxomas encroaching on the mitral annulus resulted in contrasting outcomes in two patients, ranging from successful repair to fatal multiorgan failure.

synapsesocial.com/papers/69df2b85e4eeef8a2a6b0867https://doi.org/10.1186/s13019-026-04073-1
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Surgical treatment of atrial myxomas, 6 years’ experience via standard sternotomy2012 · 1 citations
  2. 2Left Atrial Myxomectomy with Intraoperative Severe Mitral Regurgitation and Complicated Postoperative Course – Case Report2016
  3. 3Large left atrial myxoma with functional mitral stenosis: a case report2026 · 1 citations
  4. 4Superior Transseptal Approach for Surgical Removal of Left Atrial Myxoma1997 · 4 citations
  5. 5Atrial Myxomas: A Single Unit's Experience in the Modern Era2011 · 16 citations