Analysis reveals the role of genetic and environmental exposures in systemic sclerosis incidence in Canada, suggesting risk factors for future research.
The condition is associated with genetic risks (18%) and environmental and workplace exposures, including respirable crystalline silica (e.g., from construction, mining) and organic solvents (e.g., degreasers, paint thinners, adhesives).[1][1] Incidence in Canada is roughly 4 per 100 000 person-
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Osman et al. (2026) studied this question.
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