Why the study?
Does SNP rs738409 G allele increase NAFLD susceptibility and serum ALT in Asian population?
Does SNP rs738409 G allele increase NAFLD susceptibility and serum ALT in Asian population?
The PNPLA3 rs738409 G allele is a strong risk factor for NAFLD and elevated ALT in Asian populations.
Supports PNPLA3-guided risk assessment in Asian NAFLD; leaves open prospective validation of clinical utility.
This study provided evidence of SNP rs738409 G allele as a strong risk factor of NAFLD susceptibility and higher level of serum ALT in Asian population.
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Zhang et al. (2015) studied this question.
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