Demonstrates a new method to rapidly screen aptamer variants against diverse molecules, indicating improved aptamer development for various applications.
Natural aptamers control biological processes in bacteria while synthetic nucleic acid aptamers have been applied to numerous biotechnological applications. Prior to developing aptamer technologies, sequence variants and specificity must be characterized. Here, we present a highly sensitive surface plasmon resonance (SPR) method adapted to rapidly screen aptamer variants against diverse molecules.
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Ayon et al. (2024) studied this question.
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