Effect of O-acetylation on ketene and carbonyl yields from conventional and emerging cannabinoids

R. Evans; C. Noel Corley; Haylee C. Hunsaker; Sascha  CT Nicklisch; Allison Ehrlich; Tran B Nguyen

doi:10.1039/d6an00190d

January 1, 2026The Analyst

Effect of O-acetylation on ketene and carbonyl yields from conventional and emerging cannabinoids

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Key Points

The study aims to examine how o-acetylation affects the yields of ketene and carbonyl compounds from cannabinoids.
Analysis of conventional and emerging cannabinoids
Measurement of ketene and carbonyl yields
Investigation of acetylated compounds
Increased ketene yield from acetylated cannabinoids
Carbonyl yields were also affected by o-acetylation
Indications of pulmonary toxicity associated with higher yields

Implication

Research reveals the effect of o-acetylation on ketene and carbonyl yields in cannabinoids, indicating potential health risks.

Abstract

The pulmonary toxicant, ketene, has been observed from electronic (e-) cigarette vaping and dabbing (flash vaporisation) of acetylated compounds such as Vitamin E Acetate (VEA) and the O-acetates of select...

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Cite This Study

Evans et al. (2026) studied this question.

synapsesocial.com/papers/69df2c1de4eeef8a2a6b107c https://doi.org/10.1039/d6an00190d

View Full Paper

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Effect of O-acetylation on ketene and carbonyl yields from conventional and emerging cannabinoids

Key Points

Implication

Abstract

Discussion

Cite This Study

Effect of O-acetylation on ketene and carbonyl yields from conventional and emerging cannabinoids

Key Points

Implication

Abstract

Discussion

Cite This Study

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