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April 15, 2026PeerJOpen Access

Effect of vitamin D supplementation on blood lipids in patients with metabolic syndrome: a meta-analysis

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Authors

QWQ WangHHHong HuangWJWenshu Jin

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Overview

This meta-analysis evaluates vitamin D effects on blood lipids in metabolic syndrome, suggesting potential benefits for triglycerides and HDL cholesterol.

Key Points

  • This meta-analysis aims to evaluate the impact of vitamin D supplementation on blood lipid levels in patients with metabolic syndrome.
  • Conducted a search for randomized controlled trials from 1948 to February 2026.
  • Included trials where vitamin D was administered to individuals with metabolic syndrome.
  • Performed a meta-analysis on data from selected studies.
  • Vitamin D supplementation significantly reduced triglyceride levels by an average of 12.64 mg/dL.
  • No significant changes in total cholesterol or LDL cholesterol levels were found.
  • Vitamin D supplementation increased HDL cholesterol levels, especially with daily regimens, by an average of 1.77 mg/dL.

Cite This Study

Wang et al. (2026) studied this question.

synapsesocial.com/papers/69df2c1de4eeef8a2a6b10b2https://doi.org/10.7717/peerj.21086
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