Key result
Elevated CIMT correlates strongly with angiographic CAD severity and appears in 76% of patients.
Why the study?
Coronary angiography is invasive, creating a need to evaluate whether noninvasive carotid ultrasound markers correlate with coronary artery disease severity.
Does carotid ultrasound evaluation of CIMT and plaques correlate with CAD severity on coronary angiography in patients with CAD?
Cross-Sectional (n=100)
Does carotid ultrasound evaluation of CIMT and plaques correlate with CAD severity on coronary angiography in patients with CAD?
Carotid ultrasound is a useful noninvasive screening tool, as increased CIMT and carotid plaques strongly correlate with angiographic CAD severity.
Carotid ultrasound may aid noninvasive CAD severity assessment; extends evidence supporting CIMT as surrogate marker.
Introduction: Atherosclerosis is a systemic disease affecting various arteries, with coexisting carotid and coronary artery disease (CAD) leading to worse clinical outcomes. The diagnostic gold standard for CAD, coronary angiography (CAG), is an invasive procedure. Carotid ultrasound offers a noninvasive method to detect early atherosclerotic changes like increased carotid intima-media thickness (CIMT). Aim: The aim is to assess the correlation between carotid CIMT and plaque characteristics on ultrasonography (USG) with CAD severity as determined by CAG. Materials and Methods: 100 angiographically diagnosed CAD patients aged 18–80 years were subjected to ultrasound of bilateral carotid arteries for IMT and plaque evaluation. The results were compared with CAG findings. P ≤ 0.05 was considered statistically significant. Results: Elevated CIMT (≥0.8 mm) was seen in 76% of patients, with a mean CIMT of 1.048 mm. Higher CIMT was significantly associated with age, male sex, smoking, hypertension, dyslipidemia, and the presence of plaques. Carotid plaques were common at the carotid bulb, on the right side, and type 4 morphology was most frequent. CIMT and the number of plaques showed a strong correlation with CAD severity, particularly in multi-vessel disease. Conclusion: Increased CIMT and carotid plaques are significant, noninvasive markers of CAD severity. Carotid USG serves as a cost-effective screening tool for early atherosclerosis detection.
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Nanda et al. (2026) conducted a cross-sectional in Coronary Artery Disease (n=100). Carotid ultrasound (CIMT and plaque evaluation) vs. Coronary angiography was evaluated on Correlation between carotid CIMT and plaque characteristics with CAD severity. Elevated carotid intima-media thickness (≥0.8 mm) was present in 76% of CAD patients and strongly correlated with CAD severity on angiography, particularly in multi-vessel disease.
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