What question did this study set out to answer?

To explore the advancements in metabolic surgery and their implications for obesity management through precision medicine.

April 15, 2026Journal of Minimal Access Surgery0 citationsOpen Access

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The evolving landscape of metabolic surgery: An evidence-based review

VDVidit Dholakia DSDas S SNSamiran Nundy

Key Points

To explore the advancements in metabolic surgery and their implications for obesity management through precision medicine.
Reviewed current evidence on dual receptor agonists in metabolic surgery
Analyzed procedure personalization based on metabolic phenotyping
Evaluated the role of lifelong surveillance registries tailored to demographics
Indicated a shift from rigid surgical protocols to more individualized approaches
Found that integrated dual receptor therapies enhance metabolic outcomes
Demonstrated the importance of regional adaptation in surveillance strategies for effectiveness

Abstract

The MBS landscape is undergoing a paradigm shift. Optimal obesity management is evolving beyond rigid anatomical algorithms towards precision medicine, driven by the synergistic integration of dual glucagon-like peptide-1/glucose-dependent insulinotropic polypeptide receptor agonists, procedure personalisation based on metabolic phenotyping and robust lifelong surveillance registries tailored to regional demographics.

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The evolving landscape of metabolic surgery: An evidence-based review

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