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The review aims to summarize the biology of bacterial biofilms and explore therapeutic advancements for managing biofilm-associated infections.

April 15, 2026AntibioticsOpen Access

Detection to Disruption: A Comprehensive Review of Bacterial Biofilms and Therapeutic Advances

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The review aims to summarize the biology of bacterial biofilms and explore therapeutic advancements for managing biofilm-associated infections.
Comprehensive review of current literature on biofilm biology and its clinical relevance.
Examination of mechanisms contributing to biofilm tolerance and resistance.
Discussion of detection methods and therapeutic options for biofilm-related infections.
Bacterial biofilms significantly complicate treatment due to their protective matrix and heterogeneous nature.
Key resistance mechanisms include limited antibiotic diffusion and horizontal gene transfer.
Innovative treatment strategies involving various therapies are necessary for effective biofilm management.

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This review explores bacterial biofilms, their roles in infections, and therapeutic strategies, suggesting integrated management approaches.

Maroju et al. (2026) studied this question.

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This review explores bacterial biofilms, their roles in infections, and therapeutic strategies, suggesting integrated management approaches.