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April 15, 2026Pediatric Neurosurgery

Pediatric Meningiomas: Clinicopathological Spectrum, Long-Term Outcomes, and Recurrence Predictors

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Authors

JJJeena JosephSGSwaminathan GaneshKRKrishnaprabhu Raju

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Overview

Retrospective analysis reveals key predictors of recurrence in pediatric meningiomas, suggesting importance of vigilant monitoring.

Key Points

  • This study aims to analyze the clinical characteristics, treatment outcomes, and predictors of recurrence in pediatric meningiomas.
  • Retrospective analysis of 47 patients under 18 years with meningiomas treated over 20 years
  • Data collected on demographics, clinical presentation, and histopathology
  • Recurrence rate and event-free survival assessed with Kaplan–Meier estimates
  • Multivariate analyses used to identify predictors of recurrence
  • Pediatric meningiomas accounted for 3.9% of all meningiomas treated during the study period
  • High-grade meningiomas comprised 61.7% of cases
  • Gross total resection achieved in 82.9% of patients
  • Recurrence occurred in 21.3% of patients at a median follow-up of 41 months
  • Higher MIB-1 labelling index and longer follow-up duration identified as independent predictors of recurrence

Cite This Study

Joseph et al. (2026) studied this question.

synapsesocial.com/papers/69df2c9ee4eeef8a2a6b1cffhttps://doi.org/10.1159/000551876
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Pediatric meningiomas: A meta-analysis of clinical, pathological and prognostic data of 887 patients2026
  2. 2Clinical Features and Survival Outcomes of Pediatric Meningioma Patients: An Integrative Analysis Based on the SEER Database2026
  3. 3Risk Factors and Genomic Characteristics of Recurrent Meningiomas Identified Through Routine Clinical Testing2025
  4. 4Is location more determining than WHO grade for long-term clinical outcome in patients with meningioma in the first two decades of life?2024 · 1 citations
  5. 5ID #63 Pediatric Meningiomas, case series.2026