Investigation shows improved lesion dosimetry accuracy in radiopharmaceutical imaging, suggesting a promising correction method.
OR + LRD increased AD compared to OR, independent of administered radiopharmaceutical and lesion location. This study suggests that implementing LRD may be a promising option for image-based spill-over correction in ¹⁷⁷Lu-SPECT based dosimetry. Further studies are necessary to investigate the effect of different PVC methods, such as LRD or phantom-based correction factors, on overall uncertainty of lesion ADs.
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Ells et al. (2026) studied this question.
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