September 15, 2022Open Access

Autonomic function predicts cognitive decline in mild cognitive impairment: Evidence from power spectral analysis of heart rate variability in a longitudinal study

PNPaola NicoliniAmerican Society of Safety Professionals TLTiziano LucchiFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico CACarlo AbbateUniversity of Rome Tor Vergata

Structured PICO

Does autonomic function (measured by HRV) predict cognitive decline in patients with mild cognitive impairment?

Population

Patients with mild cognitive impairment (MCI)

Intervention

Power spectral analysis of heart rate variability (HRV) to assess autonomic function

Outcome

Cognitive declinesurrogate

Heart rate variability may serve as a predictor for cognitive decline in patients with mild cognitive impairment, highlighting a heart-brain connection.

Abstract

Our findings provide novel insight into the link between HRV and cognition in MCI. They contribute to a better understanding of the heart-brain connection, but will require replication in larger cohorts.

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