A series of 2,3,4‐trimethoxyacetophenoxime esters containing benzothiazole moiety were synthesized by the reaction of oxime with acyl chloride in alkaline medium. Their structures were established by elemental analysis, IR, and 1 H NMR spectra. The bioassay tests showed that these title compounds exhibit moderate anticancer activity in vitro by MTT method and compounds 6c and 6d could inhibit ERK phosphorylation in NIH 3T3 cell induced by PDGF.
No takes yet. Share an insight, caveat, or question.
Song et al. (2005) studied this question.
Synapse has enriched 5 related papers. Consider them for comparative context: