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April 1, 1998Annual Review of Immunology

JAKS AND STATS: Biological Implications

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Authors

Warren J. LeonardWarren J. LeonardNational Heart Lung and Blood InstituteJohn J. O’SheaJohn J. O’SheaWest Virginia University

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Cite This Study

Leonard et al. (1998) studied this question.

synapsesocial.com/papers/69df3e583b0ba53fb37a2245https://doi.org/10.1146/annurev.immunol.16.1.293
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Signaling by IL-2 and related cytokines: JAKs, STATs, and relationship to immunodeficiency1996 · 112 citations
  2. 2The proteins of ISGF-3, the interferon alpha-induced transcriptional activator, define a gene family involved in signal transduction.1992 · 543 citations
  3. 3Activation of STAT4 by IL-12 and IFN-α: evidence for the involvement of ligand-induced tyrosine and serine phosphorylation1996 · 275 citations
  4. 4THE IFNγ RECEPTOR:A Paradigm for Cytokine Receptor Signaling1997 · 1,039 citations
  5. 5Mutation in the Jak Kinase JH2 Domain Hyperactivates Drosophila and Mammalian Jak-Stat Pathways1997 · 246 citations