Does atrial functional mitral regurgitation have a different prognosis compared to ventricular functional mitral regurgitation?
AFMR has a better prognosis than VFMR, but this survival advantage is primarily driven by preserved LV systolic function rather than differences in mitral regurgitation severity.
AFMR is a common cause of significant functional MR that predominantly affects elderly female patients with AF. Advancing age and pulmonary hypertension independently associated with survival in FMR. Prognosis was better in AFMR compared with VFMR; however, this difference was accounted for by LV systolic impairment and not by MR severity.
Moonen et al. (Wed,) studied this question.