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January 21, 2015Gut

Tim-3 fosters HCC development by enhancing TGF-β-mediated alternative activation of macrophages

Wenjiang Yan Xiao Liu Hongxin Ma Hualin Zhang Xiaojia Song Lifen Gao Xiaohong Liang Chunhong Ma

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Abstract

Tim-3 displays critical roles in microenvironment-induced activation and protumoral effects of TAMs in HCC. Interference of Tim-3 might be great potential in HCC therapy.

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Yan et al. (2015) studied this question.

synapsesocial.com/papers/69df3e806324afb55d5919f3 https://doi.org/10.1136/gutjnl-2014-307671

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