Does intraoperative dexmedetomidine infusion reduce increases in systolic blood pressure in patients undergoing craniotomy?
Intraoperative dexmedetomidine safely blunts perioperative systolic blood pressure increases during craniotomy.
By using indices, which assess a global hemodynamic stability of the anesthetic, we determined that intraoperative DEX infusion was effective for blunting the increases in SBP perioperatively. The use of DEX did not increase the incidence of hypotension or bradycardia, common side effects of the drug.
Bekker et al. (Tue,) studied this question.