August 10, 2017Clinical Journal of the American Society of Nephrology130 citations
View Full PapereGFR and Albuminuria in Relation to Risk of Incident Atrial Fibrillation: A Meta-Analysis of the Jackson Heart Study, the Multi-Ethnic Study of Atherosclerosis, and the Cardiovascular Health Study
Structured PICO
Do reduced eGFR and elevated urine albumin-to-creatinine ratio increase the risk of incident atrial fibrillation?
P
Population
Participants from three cohorts (Jackson Heart Study, Multi-Ethnic Study of Atherosclerosis, and the Cardiovascular Health Study)
I
Intervention
Reduced eGFR and elevated urine albumin-to-creatinine ratio
O
Outcome
Incident atrial fibrillationhard clinical
Reduced kidney function and elevated albuminuria are significant risk factors for developing incident atrial fibrillation.
Abstract
In this meta-analysis of three cohorts, reduced eGFR and elevated urine albumin-to-creatinine ratio were significantly associated with greater risk of incident atrial fibrillation, highlighting the need for further studies to understand mechanisms linking kidney disease with atrial fibrillation.