Why the study?
Do combined oral contraceptives increase the risk of myocardial infarction or ischemic stroke in women?
Do combined oral contraceptives increase the risk of myocardial infarction or ischemic stroke in women?
Combined oral contraceptives are associated with a 1.6-fold increased risk of myocardial infarction or ischemic stroke, with formulations containing levonorgestrel and 30 μg of estrogen appearing to be the safest.
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May inform shared decision-making on contraception for women with CV risk factors; reinforces observational evidence without establishing causality.
Roach et al. (2015) studied this question.
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