Case report demonstrates rapid hypothalamic-pituitary-adrenal activation in early COVID-19 with vasopressin deficiency, highlighting acute neuroendocrine responses.
These findings illustrate the rapid response of the HPA axis to inflammatory factors in the early-stage COVID-19, which may have important implications for understanding the initial host responses to SARS-CoV-2 infection.
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Kirikae et al. (2025) studied this question.
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