Why the study?
Does endocardial RF catheter ablation prevent pacemaker implantation and improve symptoms in patients with severe neurally mediated reflex syncope?
Does endocardial RF catheter ablation prevent pacemaker implantation and improve symptoms in patients with severe neurally mediated reflex syncope?
Cardioneuroablation may be an effective long-term strategy to prevent pacemaker implantation and eliminate cardioinhibition in highly selected patients with severe neurally mediated syncope.
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May support avoiding pacemakers via ablation in selected reflex syncope; leaves open confirmation in randomized trials.
Endocardial RF catheter ablation of severe neurally meditated reflex syncope prevented pacemaker implantation and showed excellent long-term results in well selected patients. Despite no action in vasodepression it seems to cause enough long-term vagal reflex attenuation, eliminating the cardioinhibition, and keeping most patients asymptomatic. Indication was based on clinical symptoms, reproduction of severe cardioinhibitory syncope, and normal atropine response.
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M et al. (2011) studied this question.
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