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October 8, 2014Gut

Bone marrow Th17 TNFα cells induce osteoclast differentiation, and link bone destruction to IBD

Thomas Ciucci Lidia Ibáñez Agathe Boucoiran Eléonore Birgy-Barelli Jérôme Pène Grazia Abou‐Ezzi Nadia Arab Matthieu Rouleau Xavier Hébuterne Hans Yssel Claudine Blin‐Wakkach Abdelilah Wakkach

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Abstract

Our results highlight the osteoclastogenic function of the Th17 TNF-α(+) cells that contribute to bone loss in vivo in IBD.

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Ciucci et al. (2014) studied this question.

synapsesocial.com/papers/69dfec77de200760a861540e https://doi.org/10.1136/gutjnl-2014-306947

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