February 9, 2009Anesthesia & Analgesia

Optimal Perfusion During Cardiopulmonary Bypass: An Evidence-Based Approach

View Full Paper

Ask AI

Bookmark

Why the study?

What is the optimal management of physiologic variables and circuit components during adult cardiopulmonary bypass?

Population

Adults undergoing cardiopulmonary bypass

Comparison

Various cardiopulmonary bypass management… vs Alternative cardiopulmonary bypass management…

Design

Review

Authors

GMGlenn S. MurphySprint (United States)EHEugene A. HesselUniversity of Kentucky RGRobert C. GroomTenwek Hospital

Discussion

Member takes

Implication

Current data preclude strong CPB recommendations; leaves open optimal management pending randomized trials.

Structured PICO

What is the optimal management of physiologic variables and circuit components during adult cardiopulmonary bypass?

Population

Adults undergoing cardiopulmonary bypass

Intervention

Various cardiopulmonary bypass management strategies (e.g., MAP targets, hematocrit levels, pump flow rates, temperature, circuit components)

Comparator

Alternative cardiopulmonary bypass management strategies

Outcome

Clinical outcomes, major morbidity, and mortality

Current evidence is insufficient to make strong recommendations for optimal cardiopulmonary bypass management, highlighting the need for high-quality randomized trials.

Limitations

Limited data
Lack of randomized trials assessing clinically significant outcomes

Cite This Study

Murphy et al. (2009) studied this question.

synapsesocial.com/papers/69dfed45032653edbf7a0d2a https://doi.org/10.1213/ane.0b013e3181875e2e

View Full Paper

Ask AI

Bookmark

Optimal Perfusion During Cardiopulmonary Bypass: An Evidence-Based Approach

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Optimal Perfusion During Cardiopulmonary Bypass: An Evidence-Based Approach

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Also Consider

Also Consider