Pre-eclampsia rates in the United States, 1980-2010: age-period-cohort analysis
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Implication
Age-period-cohort analysis shows rising rates of severe pre-eclampsia among pregnant women, highlighting that obesity reduction may improve maternal and perinatal health.
Key Points
- To assess long-term trends in severe pre-eclampsia rates and evaluate the distinct contributions of age, period, and birth cohort effects.
- Conducted an age-period-cohort epidemiological analysis of severe pre-eclampsia rates from 1980 to 2010.
- Evaluated the influence of temporal risk factors, including maternal obesity, smoking trends, and evolving diagnostic criteria.
- Rates of severe pre-eclampsia increased consistently over the study period, driven by significant age, period, and birth cohort effects.
- Rising maternal obesity rates and shifts in diagnostic criteria acted as primary drivers of the observed temporal increases.
Cite This Study
Ananth et al. (2013) studied this question.