What question did this study set out to answer?

To determine how microbial species with disparate growth rates achieve stable coexistence through chemical-mediated interactions in continuous-growth environments.

May 3, 2019SHILAP Revista de lepidopterologíaOpen Access

Microbial coexistence through chemical-mediated interactions

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Authors

LNLori Niehaus IBIan Boland MLMinghao Liu

Discussion

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Overview

Modeling study demonstrates that chemical mediator turnover drives microbial coexistence in continuous-growth environments, suggesting principles for engineering stable synthetic microbiomes.

Key Points

To determine how microbial species with disparate growth rates achieve stable coexistence through chemical-mediated interactions in continuous-growth environments.
Formulated and experimentally constrained a dynamic mathematical model that explicitly tracks interaction mediators, including secreted nutrients and waste products, under constant resource inflow.
Facilitation and self-restraint directly support stable multispecies coexistence.
Under strong community interactions, coexistence is governed primarily by the network topology of facilitation and inhibition rather than absolute interaction strengths.
Active degradation or consumption of chemical mediators attenuates interaction intensity, preventing competitive exclusion.

Cite This Study

Niehaus et al. (2019) studied this question.

synapsesocial.com/papers/69dff52893e101b251e9c0d5 https://doi.org/10.1038/s41467-019-10062-x

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May 3, 2019SHILAP Revista de lepidopterologíaOpen Access

Microbial coexistence through chemical-mediated interactions

View Full Paper

Ask AI

Bookmark

Authors

LNLori Niehaus IBIan Boland MLMinghao Liu

Discussion

Member takes

Overview

Modeling study demonstrates that chemical mediator turnover drives microbial coexistence in continuous-growth environments, suggesting principles for engineering stable synthetic microbiomes.

Key Points

To determine how microbial species with disparate growth rates achieve stable coexistence through chemical-mediated interactions in continuous-growth environments.
Formulated and experimentally constrained a dynamic mathematical model that explicitly tracks interaction mediators, including secreted nutrients and waste products, under constant resource inflow.
Facilitation and self-restraint directly support stable multispecies coexistence.
Under strong community interactions, coexistence is governed primarily by the network topology of facilitation and inhibition rather than absolute interaction strengths.
Active degradation or consumption of chemical mediators attenuates interaction intensity, preventing competitive exclusion.

Cite This Study

Niehaus et al. (2019) studied this question.

synapsesocial.com/papers/69dff52893e101b251e9c0d5 https://doi.org/10.1038/s41467-019-10062-x

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