Prospective Comprehensive Genomic Profiling of Advanced Gastric Carcinoma Cases Reveals Frequent Clinically Relevant Genomic Alterations and New Routes for Targeted Therapies

Siraj M. Ali; Eric M. Sanford; Samuel J. Klempner; Douglas A. Rubinson; Kai Wang; Norma Alonzo Palma; Juliann Chmielecki; Roman Yelensky; Gary A. Palmer; Deborah Morosini; Doron Lipson; Daniel V.T. Catenacci; Fadi Braiteh; Rachel Erlich; Philip J. Stephens; Jeffrey S. Ross; Sai‐Hong Ignatius Ou; Vincent A. Miller

doi:10.1634/theoncologist.2014-0378

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Abstract

Comprehensive genomic profiling of GC identifies clinically relevant GAs that suggest benefit from targeted therapy including MET-amplified GC and ERBB2 base substitutions.

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Ali et al. (2015) studied this question.

synapsesocial.com/papers/69dff595ca6b6a2615860517 https://doi.org/10.1634/theoncologist.2014-0378

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Prospective Comprehensive Genomic Profiling of Advanced Gastric Carcinoma Cases Reveals Frequent Clinically Relevant Genomic Alterations and New Routes for Targeted Therapies

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Prospective Comprehensive Genomic Profiling of Advanced Gastric Carcinoma Cases Reveals Frequent Clinically Relevant Genomic Alterations and New Routes for Targeted Therapies

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