Two-stage study reveals nonlinear links between systemic inflammatory indices and fatty liver disease in Chinese adults, highlighting anti-inflammatory intervention potential.
Systemic immune-inflammatory indices exhibit nonlinear associations with MAFLD risk, independent of traditional metabolic factors. This reinforces MAFLD as a systemic inflammatory disease and highlights the potential of anti-inflammatory strategies, especially during the early, reversible stage before the risk plateaus.
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Zhao et al. (2025) studied this question.
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