Why the study?
Do S-endoglin concentrations increase prior to subclinical structural vascular alterations in adolescents with T1DM?
Do S-endoglin concentrations increase prior to subclinical structural vascular alterations in adolescents with T1DM?
S-endoglin may serve as an early biomarker for endothelial dysfunction prior to structural vascular changes in diabetic adolescents.
S-endoglin may flag early endothelial dysfunction in T1DM adolescents; leaves open predictive value and clinical adoption pending longitudinal data.
In adolescents with T1DM, S-endoglin concentrations might increase in parallel to the deterioration in endothelial function before subclinical structural vascular alterations become evident.
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Emeksiz et al. (2016) studied this question.
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