What does this research mean for the field?

Melatonin administration may serve as a useful adjunct in managing pediatric obesity by optimizing sleep behavior and secondarily reducing overeating, particularly in children with prenatal vulnerabilities. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To evaluate the therapeutic impact of melatonin on sleep disturbances, hyperphagia, and rapid weight gain in a school-aged child with prenatal exposure to maternal type 2 diabetes.

August 22, 2026Journal of Clinical Research in Pediatric EndocrinologyOpen Access

Melatonin Use in a School-aged Boy with Obesity Born to a Mother with Type 2 Diabetes

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Authors

ANAkihiro NakamuraNTT Medical Center

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Implication

Case report reveals melatonin improves sleep quality and aids weight reduction in pediatric obesity with prenatal diabetes exposure, indicating the value of circadian regulation.

Key Points

To evaluate the therapeutic impact of melatonin on sleep disturbances, hyperphagia, and rapid weight gain in a school-aged child with prenatal exposure to maternal type 2 diabetes.
Clinical evaluation of an 11-year-old boy presenting with rapid weight gain (62 kg, BMI z-score: 2.44) and overeating refractory to standard dietary and physical activity interventions.
Conducted endocrine evaluations and initiated oral melatonin at 1 mg/day to address severe sleep disturbances and circadian dysregulation.
Melatonin administration substantially improved sleep posture and reduced nighttime awakenings.
Treatment produced a secondary reduction in overeating episodes and resulted in gradual weight reduction without adverse events.

Cite This Study

Akihiro Nakamura (2026) studied this question.

synapsesocial.com/papers/6a895ec3ca7ade938187cdbc https://doi.org/10.4274/jcrpe.galenos.2026.2026-7-24

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Implication

Case report reveals melatonin improves sleep quality and aids weight reduction in pediatric obesity with prenatal diabetes exposure, indicating the value of circadian regulation.

Melatonin Use in a School-aged Boy with Obesity Born to a Mother with Type 2 Diabetes

Discussion

Member takes

Implication

Key Points

Cite This Study

Melatonin Use in a School-aged Boy with Obesity Born to a Mother with Type 2 Diabetes

Discussion

Member takes

Implication

Key Points

Cite This Study

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