Why the study?
Does intensive glucose control reduce major cardiovascular events, death, or microvascular complications in veterans with poorly controlled type 2 diabetes?
Does intensive glucose control reduce major cardiovascular events, death, or microvascular complications in veterans with poorly controlled type 2 diabetes?
Intensive glucose control in veterans with poorly controlled type 2 diabetes does not significantly reduce major cardiovascular events or death, but may reduce the progression of albuminuria.
Intensive glucose control should not target cardiovascular or mortality reduction in veterans with longstanding diabetes; confirms neutral macrovascular results across major trials.
Intensive glucose control in patients with poorly controlled type 2 diabetes had no significant effect on the rates of major cardiovascular events, death, or microvascular complications with the exception of progression of albuminuria (P = 0.01) [added]. (ClinicalTrials.gov number, NCT00032487.)
No takes yet. Share an insight, caveat, or question.
Duckworth et al. (2008) studied this question.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: