Why the study?
Does insulin enhance arterial endothelial function in healthy subjects compared to those with metabolic syndrome?
Population
Healthy subjects and subjects with metabolic syndrome (METSYN)
Authors
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Suggests vascular insulin resistance in metabolic syndrome; leaves open its utility for cardiovascular risk stratification or targeted therapy.
Does insulin enhance arterial endothelial function in healthy subjects compared to those with metabolic syndrome?
Vascular insulin resistance in metabolic syndrome prevents insulin-mediated enhancement of endothelial function, potentially underlying increased cardiovascular risk.
Jahn et al. (2016) studied this question.