Population
Patients with chronic renal failure (CRF)
Design
Review
Authors
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Supports mechanistic basis for uremic dyslipidemia; leaves open whether targeting LCAT or lipases alters cardiovascular or renal outcomes.
Dyslipidemia in chronic renal failure is characterized by impaired HDL maturation and triglyceride-rich lipoprotein clearance, which may contribute to increased cardiovascular risk and progression of renal disease.
Nosratola D. Vaziri (2006) studied this question.
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